Job Description

Join the Hoover Lab at Brigham and Women’s Hospital and Harvard Medical School

We are pioneering research on tissue injury and repair in autoimmunity, with a focus on lupus-related kidneys and rheumatoid arthritis ( thehooverlab.com ). Kidney injury significantly impacts morbidity and mortality in patients living with lupus, while rheumatoid arthritis affects up to 1% of the population. Using cutting-edge technologies, we study patient samples and disease models to uncover new insights and advance potential treatments with a particular focus on macrophages.

Please send your application materials (details at the bottom) to [email protected].

Job Description:

We are seeking a motivated researcher to lead experiments investigating innate immune mechanisms driving lupus-associated kidney damage and repair. You will work on innovative in vivo and in vitro studies, validating new cellular and molecular targets within a collaborative team. This will involve genomic library prep and mouse handling.

Qualifications:

• PhD, MD, or MD/PhD with an emphasis on immunology or kidney biology
• Proficiency in mouse handling, in vivo experiments, tissue harvest and processing, immune cell isolation from blood.
• Experienced with flow cytometry and immune profiling
• Proficient in genomic library preparation (bulk and single cell)

Key Responsibilities:

• Lead experiments using mouse models and human samples to understand the role of macrophages in autoimmune tissue repair and injury
• Harvest, process, and analyze tissue and blood from mouse models and human samples
• Apply genomics, flow cytometry, spatial profiling, and other advanced techniques
• Prepare genomic sequencing libraries and ensure sample quality
• Analyze and interpret data from mouse and human studies
• Collaborate, troubleshoot, and contribute to scientific publications and presentations
• Be willing to learn new techniques as needed for project development

Essential attributes:

• Highly motivated, independent, and self-starter.
• Strong organizational and troubleshooting skills
• Excellent communicator and team player
• Passionate about impactful science

Why Join Us?

Become part of an innovative, collaborative community committed to advancing understanding and treatment of autoimmune diseases. We value diversity, creativity, and dedication—your contributions can help shape future therapies.

If you are interested send the following application materials to [email protected]

1) cover letter - in the letter, please comprehensively address (a) your most significant research contribution (b) experience handling mice and (c) preparing genomic libraries - either bulk or single cell.

2) your curriculum vitae

3) at least three references relating to your scientific work

4) time frame to start

5) visa status

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